Multicolor STORM. Courtesy of chemist Xiaowei Zhuang of Harvard University.

Last year, scientists developed an optical microscopy technique enabling them to clearly see individual molecules within cells. Now, they've taken the technique, abbreviated STORM, a step further. They've identified multicolored probes that let them peer into cells and clearly see multiple cellular components at the same time, such as these microtubules (green) and small hollows called clathrin-coated pits (red). Unlike conventional methods, the multicolor STORM technique produces a crisp and high resolution picture. A sharper view of how cellular components interact will likely help scientists answer some longstanding questions about cell biology. Courtesy of chemist Xiaowei Zhuang of Harvard University.

Featured in the October 17, 2007, issue of Biomedical Beat.
High res. image (1.93 MB JPEG)