NIGMS - National Institute of General Medical Sciences
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NIGMS > About NIGMS > Budget & Financial Management > Fiscal Year 2005 Budget

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Organization Chart
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Appropriation Language
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Amounts Available for Obligation
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Justification Narrative
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Budget Mechanism Table
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Budget Authority by Activity
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Summary of Changes
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Budget Authority by Object
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Salaries and Expenses
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Significant Items in SAC Report
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Authorizing Legislation
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Appropriations History
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Detail of FTE
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Detail of Positions
 
SIGNIFICANT ITEMS IN SENATE APPROPRIATION COMMITTEE REPORT
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The following section represents FY 2004 Congressional requirements for reports and significant items derived from Senate Report 108-81. These actions discussed below are contingent on inclusion of similar language and funding in the final FY 2004 appropriation and related reports. Additional items may be transmitted at a later date as a result of the final Conference report.

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Minority Science Training Programs — The Committee continues to be pleased with the quality of NIGMS's training programs, particularly those that have a special focus on increasing the number of minority scientists such as the Minority Access to Research Careers [MARC] and Minority Biomedical Research Support [MBRS] programs. The Committee expects NIGMS to continue to support these important initiatives, and is particularly pleased that NIGMS has supported biomedical career opportunity programs for high school and undergraduate college students in conjunction with historically black health professions schools. The Committee urges continued, long-term support of this program. (p. 128)

Action taken or to be taken
Division of Minority Opportunities in Research (MORE) administers research and research training programs aimed at increasing the number of minority biomedical scientists. Specifically, the Minority Access to Research Careers (MARC) Branch offers a number of programs designed to encourage minority students to pursue training for scientific careers and the Minority Biomedical Research Support (MBRS) Branch aims to enhance the science curricula and research capabilities of faculty at institutions with substantial minority enrollments. Support for both of these important programs continues to be a priority for the Institute. In addition, NIGMS, in partnership with other NIH institutes, plans to continue to contribute funds in support of high school and undergraduate college students who are enrolled in biomedical research career opportunity programs in conjunction with historically black health professions institutions.

Item
Pharmacogenetics' Research Network — The Committee commends NIGMS for its vision in creating the Pharmacogenetics' Research Network to address the genetic bases for differences in patients' reactions to medications. Development of a deeper understanding of how genetics influences whether treatments work, don't work, orcause moderate or severe side effects is critical. This is an emerging field that will lead to a personalized approach to medicine. The Committee urges NIGMS to continue to develop and expand this field further with a strong emphasis on studying drug metabolism variation and treatment response in those disease states that affect large numbers of Americans, such as diabetes, mental illness and others. (p. 128)

Action taken or to be taken
NIGMS, and the other participating NIH institutes, plan to continue the Pharmacogenetics' Research Network with a competition to be announced in FY2004, for funding in FY2005. The broad emphasis of this initiative will remain on collecting information on drug responses and making genotype-phenotype correlations. The network currently studies drug clearance pathways, including metabolism and transport, and disease applications, ranging from cardiovascular-pulmonary diseases to mental health disorders and cancers. The renewal competition will be an open one, thus allowing applications in these and other common disease areas. The network will also maintain its focus on PharmGKB, a public database for pharmacogenetics, which is intended as a tool for researchers and should enable the field by providing data, resources, and tools.

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Pre-Disease Pathways — The Committee encourages the NIGMS to collaborate with other Institutes, including NCI and NIMH, and the Office of Behavioral and Social Sciences Research to fund research to integrate physiological knowledge of pre-disease pathways with behavioral studies. (p. 128)

Action taken or to be taken
NIGMS, in collaboration with other components of the NIH, such as the National Institute of Mental Health and the Office of Behavioral Social Sciences Research, will be participating in a working group of the Advisory Committee to the Director, NIH, which was established to identify scientific opportunities and areas of basic behavioral research that should be supported by NIH. Discussion of NIH-support of research to integrate physiological knowledge of pre-disease pathways with behavioral studies is one of many issues expected to be included in the group's discussions. The working group is scheduled to convene in the spring of 2004 and plans to issue its recommendations in the form of a report in the fall of that year.

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