García's "One Size Fits All" Solution

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Long Description: a) Research question #1: How tightly do cells stick to a surface? b) Technical obstacle: Without a patterned surface to adhere to, cells stretch out any which way when growing on a glass slide. c) New tool needed: A patterned surface to prevent cells from changing shape and shifting the position of their focal adhesions. d) Technical solution: Plates (surfaced with gold and a blend of chemicals) with indentations that hold just one cell each to provide control over where and how strongly cells stick. Photo next to text shows a microscopic close-up view of a surface constructed with tiny identations, each just big enough to hold one cell.

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