Advances in Synthetic Biology

  • Endy's synthetic T7 bacteriophage genome has "cut-and-paste" sites in its DNA

  • Many genetic devices are designed to work only in the labs in which they were made

  • There was no common framework for organizing all the components of biological machines

What purpose do these DNA sites serve?

How did Endy and his coworkers overcome this challenge, and how have they shared this knowledge with other researchers?

What did Endy do to resolve this problem?

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