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PSI Pilot Phase -- Lessons Learned

  1. Structural genomics pipelines can be constructed and scaled-up

  2. High throughput operation works for many proteins

  3. Genomic approach works for structures

  4. Bottlenecks remain for some proteins

  5. A coordinated, 5-year target selection policy must be developed

  6. Homology modeling methods need improvement

NIGMS Protein Structure Initiative

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