PSI-2 Specialized Centers
Methodology and Technology Development

• Leading toward high throughput operation for difficult proteins & problems

• Membrane proteins

• Higher eukaryote proteins, especially human

• Other major bottlenecks to high throughput

• Could focus on a subset of structural genomics tasks

• Maximum requested budgets $3M dc

• 3 to 6 awards

• Supported by NIGMS and other NIH institutes and centers

NIGMS Protein Structure Initiative

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