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Model of the Origin Recognition Complex Bound to DNA

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Cryo-electron microscopy is often used to determine the structures of large molecular complexes like the origin recognition complex (ORC), which recognizes and binds DNA to start replication, the process that copies the cell's genetic material prior to cell division. Credit: Huilin Li, Brookhaven National Laboratory and Bruce Stillman, Cold Spring Harbor Laboratory.

This page last reviewed on March 23, 2012