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Biomedical Technology Research Resources (BTRRs)

These centers create critical, often unique technology and methods at the forefront of their respective fields and apply them to a broad range of basic, translational and clinical research. This occurs through a synergistic interaction of technical and biomedical expertise, both within the centers and in intensive collaborations with other leading laboratories.

The centers serve a unique purpose in the broad context of NIH-funded research. They represent a critical mass of technological and intellectual capacity with a strong focus on service and training for outside investigators, as well as providing access to and dissemination of technologies, methods and software. Their goal is to promote the widespread and routine application of the cutting-edge technologies they develop across the full spectrum from bench to bedside.

Find a center with the capabilities you need on the BTRR Portal Site Link to external Website.

View all BTRRs

Search Results for Cryo Electron Microscopy (Cryo-EM)

National Center for Macromolecular Imaging (NCMI) Link to external Website
Stanford University
Principal Investigator: Wah Chiu, Ph.D.
NCMI is focused on extending the resolution, speed and flexibility of cryo-electron microscopy for the 3-D structure determination of biological macromolecular assemblies. The center also develops cryo-electron tomography techniques to capture molecular structures in situ.

National Resource for Automated Molecular Microscopy (NRAMM) Link to external Website
New York Structural Biology Center
Principal Investigator: Bridget O. Carragher, Ph.D. and Clinton S. Potter
NRAMM develops, tests and applies technology aimed toward completely automating the processes involved in solving macromolecular structures using cryo-electron microscopy. The goal is to establish a resource that will serve as a center for high-throughput molecular microscopy as well as for transferring this technique to the research community.

For additional information on NIGMS biomedical technology research resources, please contact:

Mary Ann Wu , Ph.D.
Health Scientist Administrator
Division of Biophysics, Biomedical Technology, and Computational Biosciences
National Institute of General Medical Sciences
National Institutes of Health
45 Center Drive MSC 6200
Bethesda, MD 20892-6200
Tel: 301-435-0787

This page last reviewed on May 1, 2018